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KMID : 0380020120270020109
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Korean Journal of Biotechnology and Bioengineering
2012 Volume.27 No. 2 p.109 ~ p.113
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Enhancement of the Stability and Solubility of Prodigiosin Using β-Cyclodextrin in Seawater
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Park Hee-Yong
Kim Tai-Kyoung
Han Se-Jong
Yim Joung-Han
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Abstract
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This research was to examine the effects of various cyclodextrins on the solubility and stability of prodigiosin in seawater. Among them, β-cyclodextrin was found to have the best efficiency and formation of the inclusion complex was saturated when prodigiosin and β-cyclodextrin were mixed in a ratio of 1：8 and shaken at 25℃ and pH 8.0 for 6 h. The maximum algicidal activity against Chattonella antiqua using the inclusion complex stored at 4℃ for 5 weeks of culture was obtained, 52.28 ± 3.41%, which was about 5.0 fold higher than that of control. Our results suggest that inclusion complexes of prodigiosin and β-cyclodextrin could serve as effective algicidal agents.
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KEYWORD
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Algicidal activity, Chattonella antiqua, Cyclodextrin, Inclusion complex, Prodigiosin
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